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The role of the government is to make regulations to force companies and organizations to protect their systems, infrastructure and information from any cyberattacks, but also to protect its own national infrastructure such as the national power-grid. A Ukrainian hacker known as Rescator broke into Target Corporation computers in 2013, stealing roughly 40 million credit cards, and then Home Depot computers in 2014, stealing between 53 and 56 million credit card numbers. Warnings were delivered at both corporations, but ignored; physical security breaches using self checkout machines are believed to have played a large role. The size of the thefts has resulted in major attention from state and Federal United States authorities and the investigation is ongoing. In 1994, over a hundred intrusions were made by unidentified crackers into the Rome Laboratory, the US Air Force's main command and research facility. Using trojan horses, hackers were able to obtain unrestricted access to R...

The addition and modification of functional groups is key when producing the wide variety of medications available within this chemical classification. These modifications are performed using conventional organic synthesis and/or biotransformation techniques. The three cyclohexane rings form the skeleton of a perhydro derivative of phenanthrene. When the two methyl groups and eight carbon side chains (at C-17, as shown for cholesterol) are present, the steroid is said to have a cholestane framework. Isomerisation at the C-21 side chain produces a parallel series of compounds, referred to as isosteroids. Because corticosteroids turn down your immune system, taking them makes you more likely to get infections. Patients are at increased risk for many types of infections, from minor fungal infections in the mouth (“thrush”, caused by Candida) to life–threatening infections such as Pneumocystis carinii pneumonia. The higher the steroid dose and the longer the duration of therapy, the gr...

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